NFL Picks Against the Spread: Week 16, 2025 – Late Games

Christian McCaffrey
2024 NFL Picks: 0-0 ($0)

NFL Picks (2023): 143-141-10 (-$6,860)
NFL Picks (2022): 154-134-8 (+$9,860)
NFL Picks (2021): 144-137-2 (-$5,365)
NFL Picks (2020): 138-124-7 (+$9,350)
NFL Picks (2019): 148-128-9 (+$1,200)
NFL Picks (2018): 140-134-12 (+$845)
NFL Picks (2017): 137-147-10 (-$4,300)
NFL Picks (2016): 148-127-10 (+$780)
NFL Picks (2015): 133-138-10 (-$3,215)
NFL Picks (2014): 143-133-7 (-$1,885)
NFL Picks (2013): 144-131-8 (+$7,825)
NFL Picks (2012): 130-145-8 (-$7,445)
NFL Picks (2011): 137-133-12 (-$1,335)
NFL Picks (2010): 144-131-8 (+$5,880)
NFL Picks (2009): 151-124-9 (+$4,235)
NFL Picks (2008): 136-125-6 (+$6,105)
NFL Picks (2007): 162-135-10 (+$3,585)
If you don’t quite understand the line, total or anything else, go to my Sports Betting FAQ.

Vegas betting action updated Dec. X, 2:00 p.m. ET. Follow @walterfootball for updates.


Go to Week 16 NFL Picks – Early Games




Individual Game Pages

NFL Picks Against the Spread: Week 16 Late Games


Atlanta Falcons (5-9) at Arizona Cardinals (3-11)
Line: Falcon by 1.5. Total: 46.5.

Sunday, Dec. 21, 4:05 PM

The Matchup. Edge: .


The Motivation. Edge: .


The Spread. Edge: .

WalterFootball.com Calculated Spread: .

Westgate Advance Point Spread: Cardinals -1.

Computer Model: .


The Vegas. Edge: None.

Percentage of money on TEAM: X% (Y bets)


The Trends. Edge: Cardinals.

  • Cardinals are 52-36 ATS at home as underdogs or favorites of less than -3 since 2007.
  • Opening Line: Falcons PK.
  • Opening Total: 44.5.
  • Weather: .




  • Week 16 NFL Pick:



    Jacksonville Jaguars (10-4) at Denver Broncos (12-2)
    Line: Broncos by 3. Total: 45.5.

    Sunday, Dec. 21, 4:05 PM

    The Matchup. Edge: .


    The Motivation. Edge: .


    The Spread. Edge: .

    WalterFootball.com Calculated Spread: .

    Westgate Advance Point Spread: Broncos -2.5.

    Computer Model: .


    The Vegas. Edge: None.

    Percentage of money on TEAM: X% (Y bets)


    The Trends. Edge: .

  • Jaguars are 71-116 ATS against non-divisional opponents since 2008.
  • Opening Line: Broncos -2.5.
  • Opening Total: 43.
  • Weather: .




  • Week 16 NFL Pick:



    Pittsburgh Steelers (7-6) at Detroit Lions (8-6)
    Line: Lions by 7. Total: 49.5.

    Sunday, Dec. 21, 4:25 PM

    The Matchup. Edge: .


    The Motivation. Edge: .


    The Spread. Edge: .

    WalterFootball.com Calculated Spread: .

    Westgate Advance Point Spread: Lions -6.

    Computer Model: .


    The Vegas. Edge: None.

    Percentage of money on TEAM: X% (Y bets)


    The Trends. Edge: TBA.

  • Mike Tomlin is 66-39 ATS as an underdog.
  • Steelers are 44-22 ATS in December/January home games since 2000.
  • Mike Tomlin is 14-2 ATS after losing by 20+. ???
  • Aaron Rodgers is 138-104* ATS since 2009.
  • Aaron Rodgers is 33-27* ATS as an underdog.
  • Aaron Rodgers is 45-29 ATS after a loss (14-8 ATS as a favorite of 7.5+). ???
  • Dan Campbell is 15-5 ATS after a loss since his second season.
  • Opening Line: Lions -6.
  • Opening Total: 49.5.
  • Weather: .




  • Week 16 NFL Pick:



    Las Vegas Raiders (2-12) at Houston Texans (9-5)
    Line: Texans by 14. Total: 37.5.

    Sunday, Dec. 21, 4:25 PM

    The Matchup. Edge: .


    The Motivation. Edge: .


    The Spread. Edge: .

    WalterFootball.com Calculated Spread: .

    Westgate Advance Point Spread: Texans -12.5.

    Computer Model: .


    The Vegas. Edge: None.

    Percentage of money on TEAM: X% (Y bets)


    The Trends. Edge: Raiders.

  • Raiders are 20-15 ATS as double-digit underdogs since 2008.
  • Opening Line: Texans -11.5.
  • Opening Total: 37.5.
  • Weather: Dome.




  • Week 16 NFL Pick:



    New England Patriots (11-3) at Baltimore Ravens (7-7)
    Line: Ravens by 2.5. Total: 48.5.

    Sunday, Dec. 21, 8:20 PM

    The Matchup. Edge: .


    The Motivation. Edge: .


    The Spread. Edge: .

    WalterFootball.com Calculated Spread: .

    Westgate Advance Point Spread: Ravens by 2.

    Computer Model: .


    The Vegas. Edge: None.

    Percentage of money on TEAM: X% (Y bets)


    The Trends. Edge: None.

  • Opening Line: Ravens -1.
  • Opening Total: 47.5.
  • Weather: .




  • Week 16 NFL Pick:



    San Francisco 49ers (10-4) at Indianapolis Colts (8-6)
    Line: 49ers by 5.5. Total: 46.5.

    Monday, Dec. 22, 8:15 PM

    The Matchup. Edge: .


    The Motivation. Edge: .


    The Spread. Edge: .

    WalterFootball.com Calculated Spread: .

    Westgate Advance Point Spread: 49ers -6.5.

    Computer Model: .


    The Vegas. Edge: None.

    Percentage of money on TEAM: X% (Y bets)


    The Trends. Edge: 49ers.

  • 49ers are 45-33 ATS as favorites in night games since 1989.
  • Opening Line: 49ers -5.5.
  • Opening Total: 46.
  • Weather: .




  • Week 16 NFL Pick:




    Prop/Teaser/Parlay Picks
    A list of some of my favorite team/player prop picks this week
    (Offense & defensive ROY picks to be counted whenever winners are announced.) Picks carried over on a week-to-week basis will be in black.


    NFL Picks Week 16 – Early Games

    Individual Game Pages




    Comments on the 2025 NFL Season’s Games and Picks


    NFL Picks - Sept. 11


    Fantasy Football Rankings - Sept. 7


    2024 NFL Mock Draft - July 25


    NFL Power Rankings - June 2





    Review Walt’s Past Record Picking Games

    On the bottom half of our NFL Weekly Lander page is the history of picks Walt maintains. Walt’s Results