2025 NFL Picks – Week 10: Other Games
NFL Picks Week 10 – Early Games
NFL Picks Week 10 – Late Games
Detroit Lions (5-3) at Washington Redskins (3-6)
Line: Lions by 7.5. Total: 49.
Sunday, Nov. 9, 4:25 PM
The Matchup. Edge: Lions.

If you’re looking to bet legally, you can get the best sportsbook promos where you’ll get hundreds of dollars in free wagers if you sign up using the links on this page.
WASHINGTON OFFENSE: We’ll begin with the Redskins offense because that’s where all the changes are this week. I’m referring to Jayden Daniels, of course. Daniels dislocated his elbow and will miss extensive time. Marcus Mariota will start instead.
Mariota is capable of playing well against poor competition, as we saw when he posted 41 points against the Raiders earlier this season. However, backups like Mariota are often a horrible bet when battling top-10 defenses. The Lions are certainly a top-10 defense. In fact, they’re ranked No. 1 overall in EPA. Their defense is capable of placing plenty of pressure on the quarterback, so that’s something that will bother Mariota. Of course, Mariota’s receiver corps is in question as well. Terry McLaurin and others are sidelined, so Mariota won’t have too many options at his disposal.
Mariota won’t be able to lean on the run either. The Lions typically have a strong run defense, though they’re ranked 12th at the moment. Still, with the Detroit defenders playing closer to the line of scrimmage with Mariota under center instead of Daniels, it’s unlikely that Jacory Croskey-Merritt will find much running room.
DETROIT OFFENSE: The Lions got off to a nice start against the Vikings, but couldn’t do much after that. The reason is that Detroit lost three offensive linemen to injuries. Rookie guard Christian Mahogany was lost for the year, while tackles Penei Sewell and Taylor Decker were knocked out for the game. When asked about their availability for the game, Dan Campbell said they’re both “touch and go,” and that they wouldn’t practice on Wednesday.
We’ll see if Sewell and/or Decker can play in this game. If both are out, the Lions will have issues moving the ball. Sure, the Redskins don’t have much of a pass rush, but even they were able to dismantle the Chargers offense when Joe Alt was sidelined several weeks ago. Sure, Dorance Armstrong is out now, but it doesn’t seem like the Lions can function without both of their tackles. They have just one other natural tackle on their roster.
If, however, the Lions can get at least one of their tackles back from injury, they’ll be perfectly fine. Washington has a putrid defense that can’t stop anything. The team has an awful secondary that just got worse with Marshon Lattimore’s season-ending injury. With no pass rush to speak of, the Redskins will allow big gains to Jared Goff, if protected. Meanwhile, the Lions will pick up big chunks of yardage on the ground with their two talented backs.
RECAP: If the Lions get one of their tackles back from injury, I will definitely be betting the Lions for a high unit count. There is a massive talent discrepancy on both sides of the ball. Mariota will be a huge liability against a strong defense, especially with no receivers and poor blocking. Washington’s defense, meanwhile, will not be able to do anything to stop the Lions.
This has all the makings of the massacre, and we even have incentive on Detroit’s side. The Lions are coming off a divisional loss and will be eager to rebound so they can avoid dropping to 5-4.
Also, this line is just wrong. Assuming the Lions have at least one tackle, they should be lined at close to two touchdowns. I made this spread -13.5, and yet the spread isn’t even -10! It seems as though the oddsmakers haven’t made the correct adjustment for how bad the Redskins are. They were just +3 versus the Seahawks, for crying out loud. Let’s take advantage of this with a huge play on Detroit, as long as either Sewell or Decker plays.
THURSDAY THOUGHTS: I’ve been considering this as my October NFL Pick of the Month, in addition to the Pittsburgh pick. What I need to see is either Penei Sewell or Taylor Decker practicing enough to play. We’ll see what the injury report looks like by the end of the week.
SATURDAY NOTES: Great news: Penei Sewell will play. Taylor Decker is questionable, so he has a shot to suit up as well. The Lions will be my October NFL Pick of the Month.
ALT LINE: We’re going with the Lions -20.5 alt line because this figures to be extremely lopsided. The best line is -20.5 +390 at FanDuel. Get $200 in bonus bets from FanDuel
SUNDAY MORNING NOTES: I don’t know why the sharps are on the Redskins, but this line has moved to +7.5. I’m not worried about it.
The Motivation. Edge: Lions.
The Lions are the better team coming off a loss.
The Spread. Edge: Lions.

WalterFootball.com Calculated Spread: Lions -13.5.
Westgate Advance Point Spread: Lions -3.5.
Computer Model: Lions -10.
The Vegas. Edge: Lions.

People love the Lions.
Percentage of money on Detroit: 91% (125,000 bets)
The Trends. Edge: Lions.

Lions -7.5 (8 Units – October NFL Pick of the Month)
Under 49 (0 Units)
Alt Line: Lions -20.5 +390 (1 Unit) – FanDuel Get $200 in bonus bets from FanDuel
2025 NFL Picks – Week 10: Other Games
Comments on the 2025 NFL Season’s Games and Picks
Review Walt’s Past Record Picking Games
On the bottom half of our NFL Weekly Lander page is the history of picks Walt maintains. Walt’s Results
