NFL Matchup Hub 2026 › Week 5 matchup

Buffalo Bills at Los Angeles Rams

Week 5 · Mon, Oct 12 · Line: Rams -3 (Circa)

Every number below comes from the two team pages. The highlighted side and the arrow mark the better number in each row; ties are marked even, n/a = nothing to compare yet. No predictions.

Side by side

BillsRams
#2Power rank ◀#3
3-1Record (straight up) ◀2-2
3-1Against the spread ◀2-2
1-0on the roadATS on the road / at home even1-0at home
0-0as underdogATS as favorite / underdog n/a2-2as favorite
+0.1pts per gameAvg. cover margin ◀-3.6pts per game
+20Point differential ◀+2
14.2avg. opp. rankStrength of schedule so far ▶13.2avg. opp. rank
#18Net EPA rank ▶#2

Strength of schedule: average power rank of opponents at kickoff, lower = tougher, so the tougher schedule is marked. EPA ranks: Weeks 2-5, #1 is best on both sides of the ball.

Bills offense vs. Rams defense

Bills offenseRams defense
#3EPA per play ▶#2
#7Dropback EPA ▶#2
#1Rush EPA ◀#4
#4Success rate ▶#2

Rams offense vs. Bills defense

Bills defenseRams offense
#29EPA per play ▶#9
#28Dropback EPA ▶#13
#22Rush EPA ▶#5
#29Success rate ▶#8

Season so far

Every game in order, Week 1 first. Opp. rank = where I had the opponent in my power rankings in effect at kickoff. Recaps are mine, word for word.

Opponent's group in my power rankings at kickoff: Group A Group B Group C Group D Group F

Buffalo Bills

Week 1Sun, Sep 13 at Houston Texans Opp. rank #6Group B
W 36-31 Line -0.5 ATS: Covered (+4.5)

Bills 36, TEXANS 31 (HOU +0.5). This was a back-and-forth thriller with big plays by both teams on both sides of the ball. The Texans forgot to run the ball in the second half and Kamari Lassiter dropped a game-sealing interception. The Texans had a chance to win at the end, but the Bills sacked C.J. Stroud twice in the red zone. 409-381 BUF, 7.9-5.2 BUF

Week 2Thu, Sep 17 vs. Detroit Lions Opp. rank #12Group B
W 41-31 Line -5.5 ATS: Covered (+4.5)

BILLS 41, Lions 31 (BUF -5.5). The Lions repeatedly shot themselves in the foot with penalties, while the offensive line couldn't block because three linemen were sidelined. The Lions were down 27-7 and got most of their yardage in garbage time. 446-355 BUF, 6.5-5.7 BUF

Week 3Sun, Sep 27 vs. Los Angeles Chargers Opp. rank #25Group D
W 24-16 Line -7 ATS: Covered (+1)

BILLS 24, Chargers 16 (BUF -7). The Bills made plenty of mistakes in the first half with a James Cook fumble and two Justin Herbert interceptions, but the Chargers couldn't capitalize on them and then made mistakes in the second half. 350-348 BUF, 5.6-5.4 BUF

Week 4Sun, Oct 4 vs. New England Patriots Opp. rank #14Group C
L 26-29 Line -6.5 ATS: Did not cover (-9.5)

Patriots 29, BILLS 26 (BUF -6.5). Drake Maye lost a fumble but was otherwise back to 2025 form with his passing and rushing. This was a back-and-forth game with the Patriots scoring late to go up three and then Josh Allen, missing D.J. Moore who got hurt, throwing an interception. 405-340 NE, 6.3-5.5 BUF

Los Angeles Rams

Week 1Thu, Sep 10 vs. San Francisco 49ers (neutral) Opp. rank #8Group B
L 7-27 Line -4 ATS: Did not cover (-24)

49ers 27, Rams 7 (LAR -4). This was an even game in the first half, but the 49ers controlled the ball in the second half, as the Rams looked exhausted from traveling 24 hours beforehand, whereas the 49ers traveled a week earlier. 379-290 SF, 5.9-5.1 SF

Week 2Mon, Sep 21 vs. New York Giants Opp. rank #17Group C
W 28-6 Line -7 ATS: Covered (+15)

RAMS 28, Giants 6 (LAR -7). Jaxson Dart got hurt on the first drive and Jameis Winston struggled in relief. The Matthew Stafford to Davante Adams connection was lethal all night. 481-182 LAR, 8.0-3.3 LAR

Week 3Sun, Sep 27 at Denver Broncos Opp. rank #13Group C
L 26-30 Line -2.5 ATS: Did not cover (-6.5)

BRONCOS 30, Rams 26 (DEN +2.5). The Rams were up 16-0 at halftime and were in complete control, but the Broncos caught fire in the second half. The Rams went up 26-23, but the officials gave the Broncos a win on a silver platter with a horrible call at the end. 482-257 LAR, 5.9-4.3 LAR

Week 4Sun, Oct 4 at Philadelphia Eagles Opp. rank #15Group C
W 24-20 Line -3 ATS: Covered (+1)

Rams 24, EAGLES 20 (PHI +3). The Eagles played terribly for most of the game, but had a 20-10 lead because the Rams made so many mistakes. The Eagles couldn't maintain their lead because they were 0-of-12 on third down. The Rams stormed back with two touchdowns in the fourth quarter. 415-172 LAR, 5.4-3.0 LAR

Injuries

Buffalo Bills

WR/TE

  • Keon Coleman DDL 3 (in)
  • D.J. Moore LDL 3 (in)

Int DL

  • Ed Oliver out 2
  • Ed Oliver DL 3 (in)

CBs

  • Christian Benford DDD 4

Los Angeles Rams

WR/TE

  • Puka Nacua out 2-3
  • Colby Parkinson DDD 3-4 (out)
  • Puka Nacua returns 4
  • Terrance Ferguson out 4-IR

Int DL

  • Aaron Donald out 1
  • Aaron Donald returns 2
  • Aaron Donald out 4

Pass Rush

  • Myles Garrett out 2-IR

Key: F = Full in practice · L = Limited in practice · D = Did not practice · IR = Injured Reserve · PUP = Physically unable to perform · CE = Commissioner's Exempt List. Numbers are game weeks.