October 13, 2026

NFL Matchup Hub 2026 › Week 6 matchup

Arizona Cardinals at Los Angeles Rams

Week 6 · Sun, Oct 18 · Line: Rams -12.5 (Circa)

Arizona Cardinals logoArizona Cardinals#27 Group DAway · Team page › Los Angeles Rams logoLos Angeles Rams#3 Group AHome · Team page ›

Every number below comes from the two team pages. The highlighted side and the arrow mark the better number in each row; ties are marked even, n/a = nothing to compare yet. No predictions.

Side by side

CardinalsRams
#27Power rank ▶#3
1-4Record (straight up) ▶2-2
2-3Against the spread ▶2-2
2-1on the roadATS on the road / at home ▶1-0at home
2-2as underdogATS as favorite / underdog even2-2as favorite
-6pts per gameAvg. cover margin ▶-3.6pts per game
-54Point differential ▶+2
10.6avg. opp. rankStrength of schedule so far ◀13.2avg. opp. rank
#30Net EPA rank ▶#2

Strength of schedule: average power rank of opponents at kickoff, lower = tougher, so the tougher schedule is marked. EPA ranks: Weeks 2-5, #1 is best on both sides of the ball.

Cardinals offense vs. Rams defense

Cardinals offenseRams defense
#26EPA per play ▶#2
#26Dropback EPA ▶#2
#23Rush EPA ▶#4
#12Success rate ▶#2

Rams offense vs. Cardinals defense

Cardinals defenseRams offense
#26EPA per play ▶#9
#32Dropback EPA ▶#13
#15Rush EPA ▶#5
#23Success rate ▶#8

Season so far

Every game in order, Week 1 first. Opp. rank = where I had the opponent in my power rankings in effect at kickoff. Recaps are mine, word for word.

Opponent's group in my power rankings at kickoff: Group A Group B Group C Group D Group F

Arizona Cardinals

Week 1Sun, Sep 13 at Los Angeles Chargers Opp. rank #4Group A
W 26-14 Line +8.5 ATS: Covered (+20.5)

Cardinals 26, CHARGERS 14 (LAC -8.5). The Chargers were the better team, dominating in all three facets. They controlled the clock, which frustrated Justin Herbert, especially after losing Ladd McConkey. 393-268 ARZ, 5.5-5.3 ARZ

Week 2Sun, Sep 20 vs. Seattle Seahawks Opp. rank #9Group B
L 7-31 Line +4 ATS: Did not cover (-20)

Seahawks 31, CARDINALS 7 (ARZ +4). The Seahawks hit a big play to Jaxon Smith-Njigba to start the game, and then the Cardinals tied. Arizona could do nothing in the second half due to immense Seattle pressure, and Drew Lock once again hit Smith-Njigba twice more for touchdowns. 381-151 SEA, 5.7-3.2 SEA

Week 3Sun, Sep 27 at San Francisco 49ers Opp. rank #1Group A
L 30-36 Line +8.5 ATS: Covered (+2.5)

49ERS 36, Cardinals 30 (SF -8.5). The 49ers had great offenive production in this game until Mike Evans and Trent Williams got hurt. The 49ers were up big, but Jacoby Brissett garbage time and a muffed punt made this game close. 437 SF, 8.7-4.5 SF

Week 4Sun, Oct 4 at New York Giants Opp. rank #27Group D
L 24-36 Line -2.5 ATS: Did not cover (-14.5)

GIANTS 36, Cardinals 24 (NYG +2.5). The Giants were down 14-3 early but stormed back with the help of some Jacoby Brissett interceptions. The Cardinals and Giants then exchanged leads and it looked like the Cardinals would win at the end, but Brissett threw a pick-six on the final play of the game. 319-270 NYG, 5.2-4.3 NYG

Week 5Sun, Oct 11 vs. Detroit Lions Opp. rank #12Group B
L 21-45 Line +5.5 ATS: Did not cover (-18.5)

Lions 45, CARDINALS 21 (ARZ +5.5). The Cardinals went up early with a touchdown drive and the Lions had two scoreless possessions. After that, Detroit couldn't stop scoring. The Cardinals couldn't keep up and got two touchdowns in garbage time. 412-327 DET, 6.3-4.6 DET

Los Angeles Rams

Week 1Thu, Sep 10 vs. San Francisco 49ers (neutral) Opp. rank #8Group B
L 7-27 Line -4 ATS: Did not cover (-24)

49ers 27, Rams 7 (LAR -4). This was an even game in the first half, but the 49ers controlled the ball in the second half, as the Rams looked exhausted from traveling 24 hours beforehand, whereas the 49ers traveled a week earlier. 379-290 SF, 5.9-5.1 SF

Week 2Mon, Sep 21 vs. New York Giants Opp. rank #17Group C
W 28-6 Line -7 ATS: Covered (+15)

RAMS 28, Giants 6 (LAR -7). Jaxson Dart got hurt on the first drive and Jameis Winston struggled in relief. The Matthew Stafford to Davante Adams connection was lethal all night. 481-182 LAR, 8.0-3.3 LAR

Week 3Sun, Sep 27 at Denver Broncos Opp. rank #13Group C
L 26-30 Line -2.5 ATS: Did not cover (-6.5)

BRONCOS 30, Rams 26 (DEN +2.5). The Rams were up 16-0 at halftime and were in complete control, but the Broncos caught fire in the second half. The Rams went up 26-23, but the officials gave the Broncos a win on a silver platter with a horrible call at the end. 482-257 LAR, 5.9-4.3 LAR

Week 4Sun, Oct 4 at Philadelphia Eagles Opp. rank #15Group C
W 24-20 Line -3 ATS: Covered (+1)

Rams 24, EAGLES 20 (PHI +3). The Eagles played terribly for most of the game, but had a 20-10 lead because the Rams made so many mistakes. The Eagles couldn't maintain their lead because they were 0-of-12 on third down. The Rams stormed back with two touchdowns in the fourth quarter. 415-172 LAR, 5.4-3.0 LAR

Week 5Mon, Oct 12 vs. Buffalo Bills Opp. rank #2Group A
Not played yet · Circa line -3

Injuries

Arizona Cardinals

RBs

  • Jeremiyah Love LLL 1 (in)

WR/TE

  • Marvin Harrison Jr. out 5

OL

  • Chase Bisontis out 1-IR
  • Isaiah Adams out 1
  • Isaiah Adams LLL 2 (returns)
  • Isaac Seumalo DLL 2 (in)
  • Paris Johnson out 5-IR
  • Isaiah Adams out 5

Int DL

  • Roy Lopez LDL 2 (in)
  • Roy Lopez DDL 3 (in)
  • Walter Nolen FLL 5

Pass Rush

  • Josh Sweat DFL 4 (in)

CBs

  • Garrett Williams out 1-2
  • Max Melton LLL 2 (in)
  • Garrett Williams returns 3
  • Max Melton DLL 3 (in)

Safeties

  • Andrew Wingard out 5

Los Angeles Rams

WR/TE

  • Puka Nacua out 2-3
  • Colby Parkinson DDD 3-4 (out)
  • Puka Nacua returns 4
  • Terrance Ferguson out 4-IR

Int DL

  • Aaron Donald out 1
  • Aaron Donald returns 2
  • Aaron Donald out 4

Pass Rush

  • Myles Garrett out 2-IR

Key: F = Full in practice · L = Limited in practice · D = Did not practice · IR = Injured Reserve · PUP = Physically unable to perform · CE = Commissioner's Exempt List. Numbers are game weeks.

All Week 6 matchups · Arizona Cardinals team page · Los Angeles Rams team page