Below are players I'll be targeting on the waiver wire this week. As usual, I'm using the 50-percent(ish) ownership threshold at Yahoo to determine who is allowed on the list.
Players are listed in the order I would assign waiver priority for each position.
Samaje Perine, Redskins (13 percent)
Perine has yet to show enough to say he will be successful, but he has the ability, and now he will get his shot with Rob Kelley out with a rib injury. I like Perine's skill set well enough to invest in him at this point in the season, with the hopes that he will keep the No. 1 role moving forward.
Chris Carson, Seahawks (25 percent)
Carson was the clear lead back against the 49ers with Eddie Lacy a healthy scratch and Thomas Rawls only getting five carries for four yards. Carson, meanwhile, ran 20 times for 93 yards and caught one of two targets. Rawls and C.J. Prosise will cut into his workload, but Carson is the only back to have shown the ability to run behind this inept offensive line.
Chris Thompson, Redskins (50 percent)
Thompson has looked amazing this season, but he's also only touched the ball 13 times for his three touchdowns. That won't keep up, even if he sees an expanded role. But he's going to stay as the receiving back and Perine/Kelley will remain the early-down backs, so I'd only add him in PPR leagues unless your standard league is deep.
D'Onta Foreman (6 percent)
Lamar Miller is going to be in a full-blown committee sooner or later, and it appears it will be sooner. Foreman is showing more burst than Miller and will continue to see touches, especially as this offense sputters without an accurate passer.
Alvin Kamara, Saints (26 percent)
Kamara isn't going to be the lead back, but with the way this Saints team is going, he may have one of the more productive positions, as the receiving back. The Saints aren't going to be able to stop even the weakest offenses, so their offense will need to throw the ball early and often, likely leaving Kamara in line for some big PPR games this season.
Chris Johnson (7 percent)
This is for deeper leagues, as Johnson doesn't have much upside anymore, but he was without a doubt the best running back on the team against the Colts last week and will probably get the starts moving forward.
J.J Nelson, Cardinals (20 percent)
Nelson has looked great so far and continues to win work as the season develops. He should continue to be a factor even if/when John Brown returns, but for now, Nelson should be in line for one of the top workloads on the team.
Tyler Lockett, Seahawks (36 percent)
Lockett saw nine targets last week, which tied for the team high. He's got talent, and if this Seahawks offense can ever get back on track, his upside is high.
Marqise Lee, Jaguars (32 percent)
Lee didn't look outstanding in Week 2, but he did lead the team with 12 targets and seven receptions. He'll need the game script to push the team to throw a lot in the fourth quarter, but that might be in the works again this season.
Rashard Higgins, Browns (2 percent)
Higgins is one of the best route runners in the league and clearly has shown that he wants to actually play football in Cleveland, which isn't always the case. He also should be heavily involved, as Corey Coleman is out with a broken hand.
Jaron Brown, Cardinals (2 percent)
As long as John Brown is out, Jaron Brown should continue to see an uptick in work. He has ability and upside, but his floor is very low, especially with the way Carson Palmer has been playing.
Allen Hurns, Jaguars (17 percent)
Hurns, like Lee, will need positive game flow to see targets, as the Jaguars would much rather run the ball, but like last week, that can happen, and Hurns has been a touchdown-maker in his career.
I like Perine's ability, plus Rob Kelley looked like hot garbage in Week 1. The Eagles' defensive line is good, so Kelley could bounce back, but I still like Perine's upside more.
Devin Funchess, Panthers (10 percent)
Funchess looked better last week than he has for much of his short career, which is due to him getting some targets with Greg Olsen out for most of the game with a broken foot. Funchess should see single coverage and be a touchdown threat moving forward.
Jermaine Kearse, Jets (7 percent)
Kearse is an odd case, but one who continues to score touchdowns and make receptions. This Jets should continue to throw the ball quite a bit due to their inept defense, but it's hard to believe Kearse will keep up his touchdowns, but could be useful in PPR leagues.
Kendall Wright, Bears (14 percent)
Wright hasn't shown much, but he is getting targets, with 10 last week for seven receptions, so his PPR usage will remain.
Benjamin Watson, Ravens (2 percent)
Watson caught all eight of his targets against the Browns for 91 yards last week. The Ravens love their tight ends, and as long as Watson is healthy, he should continue to be a factor in this offense.
Evan Engram, Giants (7 percent)
Engram is going to be very good and might not be a tight end in the future, but for now he is, and he's going to continue to be as long as Brandon Marshall and company are sucking.
Charles Clay, Bills (25 percent)
Clay didn't have much chance last week against the Panthers, and this week, he'll take on the Broncos, but he is going to have easier games and will continue to be Tyrod Taylor's security blanket.
Austin Seferian-Jenkins, Jets (2 percent)
Seferian-Jenkins will come off his suspension this week to take on the Dolphins and should quickly be inserted into the starting lineup and see targets. He's turned his life around it seems and is taking the game seriously again. It will be interesting to see how he does, but at the very least, I expect him to see targets early.
Zach Miller, Bears (5 percent)
Miller is going to continue seeing good targets as one of the few reliable pass catchers on the team. His upside is low, and his injury history portends doom, but hey, he's not bad!
Trevor Siemian, Broncos (14 percent)
Siemian has looked great so far and gets two good matchups against the Bills and Raiders the next two weeks. I still consider him a streaming option, but one that is streamable against more teams than most.
Alex Smith, Chiefs (51 percent)
Smith must feel Patrick Mahomes breathing down his neck, because he let loose in Week 1 and played one of, if not the best, game of his life. Does he really have it in him to continue this elevated play? I don't know, but if you have Carson Palmer as your starter, you might be looking to upgrade.
Jay Cutler, Dolphins (29 percent)
Cutler looked good last week in San Diego, and this week gets a great matchup with the Jets, who have allowed the third-most fantasy points to quarterbacks this season.
Deshaun Watson, Texans (13 percent)
Watson is going to make plenty of mistakes, but we saw what he can do with his legs. If he's allowed to take off more, he could have good value at an extremely cheap price.
DeShone Kizer, Browns (10 percent)
Kizer gets the Colts this week, which should make him streamable in some leagues.